Physical performance in patients treated with nocturnal hemodialysis - a systematic review of the evidence

Abstract Background Patients treated with conventional hemodialysis have poor physical performance, explained by insufficient metabolic clearance and shortage of time by time-consuming dialysis. Nocturnal hemodialysis improves metabolic control and results in increased spare time. Our aim is to inve...

Full description

Bibliographic Details
Main Authors: Manouk Dam, Peter J. M. Weijs, Frans J. van Ittersum, Brigit C. van Jaarsveld
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Nephrology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12882-019-1518-4
id doaj-4807145ab709480690e34ef28bcd072a
record_format Article
spelling doaj-4807145ab709480690e34ef28bcd072a2020-11-25T03:11:34ZengBMCBMC Nephrology1471-23692019-08-012011710.1186/s12882-019-1518-4Physical performance in patients treated with nocturnal hemodialysis - a systematic review of the evidenceManouk Dam0Peter J. M. Weijs1Frans J. van Ittersum2Brigit C. van Jaarsveld3Department of Nutrition and Dietetics, Amsterdam University Medical Centers, VU UniversityDepartment of Nutrition and Dietetics, Amsterdam University Medical Centers, VU UniversityDepartment of Nephrology, Amsterdam University Medical Centers, VU UniversityDepartment of Nephrology, Amsterdam University Medical Centers, VU UniversityAbstract Background Patients treated with conventional hemodialysis have poor physical performance, explained by insufficient metabolic clearance and shortage of time by time-consuming dialysis. Nocturnal hemodialysis improves metabolic control and results in increased spare time. Our aim is to investigate whether physical performance in nocturnal hemodialysis is superior to conventional hemodialysis. Methods A systematic search was conducted in MEDLINE, Embase, CINAHL, PhycInfo and Web of Science until January 2018. Primary outcomes were physical performance, activity, strength and muscle mass in home or in-center nocturnal hemodialysis. Methodological quality was assessed with the Newcastle-Ottawa scale. Results Ten studies met the inclusion criteria, including 2 RCTs, evaluating 526 nocturnal hemodialysis patients with a mean follow-up of 15, 3 months. The methodological quality of 4 studies was limited. Physical capacity tests were done in 3 studies with different methodology: short-physical performance battery, exercise spirometry and 6-min walk test. The latter 2 showed significant improvements in physical performance. Four studies assessed lean mass using dual-energy X-ray absorptiometry (2×) and bioelectrical impedance analysis (2×), of which 1 demonstrated increased lean body and skeletal muscle mass. In 5 studies a Quality of Life questionnaire was used, of which 2 showed improved physical component score. Conclusions The evidence on the effect of nocturnal hemodialysis on physical performance is either of insufficient methodological quality or only measures isolated aspects of physical performance. As literature emphasizes the importance of physical activity on clinical outcomes, it is necessary to conduct larger studies of high methodological quality using capacity tests for answering the question whether nocturnal hemodialysis can improve physical performance of patients with end-stage renal disease. Trial registration NTR4715, Netherlands Trial Register. Registered 30 July 2014.http://link.springer.com/article/10.1186/s12882-019-1518-4Chronic hemodialysisDialysisExerciseESRDPhysical activity
collection DOAJ
language English
format Article
sources DOAJ
author Manouk Dam
Peter J. M. Weijs
Frans J. van Ittersum
Brigit C. van Jaarsveld
spellingShingle Manouk Dam
Peter J. M. Weijs
Frans J. van Ittersum
Brigit C. van Jaarsveld
Physical performance in patients treated with nocturnal hemodialysis - a systematic review of the evidence
BMC Nephrology
Chronic hemodialysis
Dialysis
Exercise
ESRD
Physical activity
author_facet Manouk Dam
Peter J. M. Weijs
Frans J. van Ittersum
Brigit C. van Jaarsveld
author_sort Manouk Dam
title Physical performance in patients treated with nocturnal hemodialysis - a systematic review of the evidence
title_short Physical performance in patients treated with nocturnal hemodialysis - a systematic review of the evidence
title_full Physical performance in patients treated with nocturnal hemodialysis - a systematic review of the evidence
title_fullStr Physical performance in patients treated with nocturnal hemodialysis - a systematic review of the evidence
title_full_unstemmed Physical performance in patients treated with nocturnal hemodialysis - a systematic review of the evidence
title_sort physical performance in patients treated with nocturnal hemodialysis - a systematic review of the evidence
publisher BMC
series BMC Nephrology
issn 1471-2369
publishDate 2019-08-01
description Abstract Background Patients treated with conventional hemodialysis have poor physical performance, explained by insufficient metabolic clearance and shortage of time by time-consuming dialysis. Nocturnal hemodialysis improves metabolic control and results in increased spare time. Our aim is to investigate whether physical performance in nocturnal hemodialysis is superior to conventional hemodialysis. Methods A systematic search was conducted in MEDLINE, Embase, CINAHL, PhycInfo and Web of Science until January 2018. Primary outcomes were physical performance, activity, strength and muscle mass in home or in-center nocturnal hemodialysis. Methodological quality was assessed with the Newcastle-Ottawa scale. Results Ten studies met the inclusion criteria, including 2 RCTs, evaluating 526 nocturnal hemodialysis patients with a mean follow-up of 15, 3 months. The methodological quality of 4 studies was limited. Physical capacity tests were done in 3 studies with different methodology: short-physical performance battery, exercise spirometry and 6-min walk test. The latter 2 showed significant improvements in physical performance. Four studies assessed lean mass using dual-energy X-ray absorptiometry (2×) and bioelectrical impedance analysis (2×), of which 1 demonstrated increased lean body and skeletal muscle mass. In 5 studies a Quality of Life questionnaire was used, of which 2 showed improved physical component score. Conclusions The evidence on the effect of nocturnal hemodialysis on physical performance is either of insufficient methodological quality or only measures isolated aspects of physical performance. As literature emphasizes the importance of physical activity on clinical outcomes, it is necessary to conduct larger studies of high methodological quality using capacity tests for answering the question whether nocturnal hemodialysis can improve physical performance of patients with end-stage renal disease. Trial registration NTR4715, Netherlands Trial Register. Registered 30 July 2014.
topic Chronic hemodialysis
Dialysis
Exercise
ESRD
Physical activity
url http://link.springer.com/article/10.1186/s12882-019-1518-4
work_keys_str_mv AT manoukdam physicalperformanceinpatientstreatedwithnocturnalhemodialysisasystematicreviewoftheevidence
AT peterjmweijs physicalperformanceinpatientstreatedwithnocturnalhemodialysisasystematicreviewoftheevidence
AT fransjvanittersum physicalperformanceinpatientstreatedwithnocturnalhemodialysisasystematicreviewoftheevidence
AT brigitcvanjaarsveld physicalperformanceinpatientstreatedwithnocturnalhemodialysisasystematicreviewoftheevidence
_version_ 1724653616128589824