Papillon-Lefèvre Syndrome and Basal Cell Carcinoma: A Case Study

Papillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disorder characterized by palmoplantar keratoderma and early-onset periodontitis. It was first described by Papillon and Lefèvre in 1924. PLS is caused by mutations in the cathepsin-C (CTSC) gene. The development of malignant skin neoplas...

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Bibliographic Details
Main Authors: Fahad M. Alsaif, Maria A. Arafah, Rasha T. Alenazi, Ghadah F. Alotaibi
Format: Article
Published: Karger Publishers 2019-06-01
Series:Case Reports in Oncology
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