Voluntary running wheel attenuates motor deterioration and brain damage in cuprizone-induced demyelination

Voluntary running wheel attenuates motor deterioration and brain damage in cuprizone-induced demyelination

Growing data from human and animal studies indicate the beneficial effects of exercise on several clinical outcomes in patients with multiple sclerosis (MS), an autoimmune, demyelinating disease, suggesting that it may slow down the disease progression, by reducing brain damage. However, the mechani...

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Bibliographic Details
Main Authors: Georgia Mandolesi, Silvia Bullitta, Diego Fresegna, Francesca De Vito, Francesca Romana Rizzo, Alessandra Musella, Livia Guadalupi, Valentina Vanni, Mario Stampanoni Bassi, Fabio Buttari, Maria Teresa Viscomi, Diego Centonze, Antonietta Gentile
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Neurobiology of Disease
Subjects:
Demyelination
Multiple sclerosis
Exercise
Cuprizone
Astrogliosis
Microgliosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118302171

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http://www.sciencedirect.com/science/article/pii/S0969996118302171

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