Modification of Low Molecular Weight Polysaccharides from Tremella Fuciformis and Their Antioxidant Activity in Vitro

In this study, sulfated low molecular-weight Tremella fuciformis polysaccharides(SLTP) with different sulfate contents were synthesized and their antioxidant activities,including superoxide anion radical, 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical andhydroxyl radical scavenging activities were in...

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Bibliographic Details
Main Authors: Bao Yang, Zheng-Xiang Ning, Cheng Zheng, Qiong Wu
Format: Article
Language:English
Published: MDPI AG 2007-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/8/7/670/
Description
Summary:In this study, sulfated low molecular-weight Tremella fuciformis polysaccharides(SLTP) with different sulfate contents were synthesized and their antioxidant activities,including superoxide anion radical, 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical andhydroxyl radical scavenging activities were investigated. The results indicated that,compared to natural Tremella fuciformis polysaccharide (TP) and low molecular weightTremella fuciformis polysaccharide (LTP), sulfated LTP (SLTP) exhibited strongerscavenging activity towards superoxide anion, DPPH and hydroxyl radicals. In all the casesthe effect was found to be dose dependent. The scavenging activity of SLTP was found tobe in parallel with the degree of sulfation of SLTP.
ISSN:1422-0067