Influenza NA and PB1 Gene Segments Interact during the Formation of Viral Progeny: Localization of the Binding Region within the PB1 Gene

Influenza NA and PB1 Gene Segments Interact during the Formation of Viral Progeny: Localization of the Binding Region within the PB1 Gene

The influenza A virus genome comprises eight negative-sense viral RNAs (vRNAs) that form individual ribonucleoprotein (RNP) complexes. In order to incorporate a complete set of each of these vRNAs, the virus uses a selective packaging mechanism that facilitates co-packaging of specific gene segments...

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Bibliographic Details
Main Authors: Brad Gilbertson, Tian Zheng, Marie Gerber, Anne Printz-Schweigert, Chi Ong, Roland Marquet, Catherine Isel, Steven Rockman, Lorena Brown
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Viruses
Subjects:
influenza virus
packaging
reassortment
RNA-RNA interaction
gene segments
viral polymerase
competitive transfection
Online Access:http://www.mdpi.com/1999-4915/8/8/238

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http://www.mdpi.com/1999-4915/8/8/238

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