Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans

The development of reliable measures of health in ageing organisms is a need in ageing research. Using atomic force microscopy, here, the authors assess whole body stiffness of worms and show that it reflects organismal fitness.

Bibliographic Details
Main Authors: Clara L. Essmann, Daniel Martinez-Martinez, Rosina Pryor, Kit-Yi Leung, Kalaivani Bala Krishnan, Prudence Pokway Lui, Nicholas D. E. Greene, André E. X. Brown, Vijay M. Pawar, Mandayam A. Srinivasan, Filipe Cabreiro
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14785-0