Designed DNA-Encoded IL-36 Gamma Acts as a Potent Molecular Adjuvant Enhancing Zika Synthetic DNA Vaccine-Induced Immunity and Protection in a Lethal Challenge Model

Identification of novel molecular adjuvants which can boost and enhance vaccine-mediated immunity and provide dose-sparing potential against complex infectious diseases and for immunotherapy in cancer is likely to play a critical role in the next generation of vaccines. Given the number of challengi...

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Bibliographic Details
Main Authors: Lumena Louis, Megan C. Wise, Hyeree Choi, Daniel O. Villarreal, Kar Muthumani, David B. Weiner
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Vaccines
Subjects:
DNA
Online Access:https://www.mdpi.com/2076-393X/7/2/42