Mefloquine Inhibits Esophageal Squamous Cell Carcinoma Tumor Growth by Inducing Mitochondrial Autophagy

Mefloquine Inhibits Esophageal Squamous Cell Carcinoma Tumor Growth by Inducing Mitochondrial Autophagy

Esophageal squamous cell carcinoma (ESCC) has a worldwide impact on human health, due to its high incidence and mortality. Therefore, identifying compounds to increase patients' survival rate is urgently needed. Mefloquine (MQ) is an FDA-approved anti-malarial drug, which has been reported to i...

Full description

Bibliographic Details
Main Authors: Yifei Xie, Jing Zhang, Bingbing Lu, Zhuo Bao, Jimin Zhao, Xianyu Lu, Yaxing Wei, Ke Yao, Yanan Jiang, Qiang Yuan, Xiaofan Zhang, Bo Li, Xinhuan Chen, Zigang Dong, Kangdong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
esophageal squamous cell carcinoma (ESCC)
mefloquine (MQ)
mitochondria
autophagy
succinate dehydrogenase complex subunit C (SDHC)
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01217/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01217/full

Similar Items