Screening for Diabetes Mellitus among Tuberculosis Patients: Findings from a Study at a Tertiary Hospital in Lusaka, Zambia

Background. Diabetes mellitus (DM) is known to be associated with active tuberculosis (TB). Zambia is a low-income sub-Saharan African country with a high TB burden and increasing numbers of newly diagnosed DM patients. Materials and Methods. This was an observational study conducted at the Universi...

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Main Authors: Sombo Fwoloshi, Lottie M. Hachaambwa, Kaseya O. Chiyeñu, Lameck Chirwa, Thijs W. Hoffman, Owen Ngalamika, Sarah Lou Bailey
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2018/3524926
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spelling doaj-4a715b18fa13482a83ba14d87ca9ac7c2021-07-02T02:57:01ZengHindawi LimitedCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932018-01-01201810.1155/2018/35249263524926Screening for Diabetes Mellitus among Tuberculosis Patients: Findings from a Study at a Tertiary Hospital in Lusaka, ZambiaSombo Fwoloshi0Lottie M. Hachaambwa1Kaseya O. Chiyeñu2Lameck Chirwa3Thijs W. Hoffman4Owen Ngalamika5Sarah Lou Bailey6Adult Infectious Diseases Center of Excellence, Department of Medicine, University Teaching Hospital, University of Zambia School of Medicine, Lusaka, ZambiaDepartment of Infectious Diseases, University of Maryland, Baltimore, MD, USADepartment of Medicine, Livingstone Central Hospital, Livingstone, ZambiaAdult Infectious Diseases Center of Excellence, Department of Medicine, University Teaching Hospital, University of Zambia School of Medicine, Lusaka, ZambiaAdult Infectious Diseases Center of Excellence, Department of Medicine, University Teaching Hospital, University of Zambia School of Medicine, Lusaka, ZambiaDermatology and Venereology Section, University Teaching Hospital, University of Zambia School of Medicine, Lusaka, ZambiaTB Centre and Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UKBackground. Diabetes mellitus (DM) is known to be associated with active tuberculosis (TB). Zambia is a low-income sub-Saharan African country with a high TB burden and increasing numbers of newly diagnosed DM patients. Materials and Methods. This was an observational study conducted at the University Teaching Hospital in Lusaka, Zambia, from October 2014 to February 2016. Adult patients with active TB were screened for DM. Results. A total of 127 individuals were enrolled in the study. Six patients (5%) were found to have diabetes. Of these, three had a prior diagnosis of diabetes and were on medication while three were newly diagnosed. Low education level was significantly associated with DM (p=0.001; 95% CI 0.001–0.148). Conclusion. The prevalence of DM among individuals with smear positive TB in our study population was similar to that of the general population in Zambia.http://dx.doi.org/10.1155/2018/3524926
collection DOAJ
language English
format Article
sources DOAJ
author Sombo Fwoloshi
Lottie M. Hachaambwa
Kaseya O. Chiyeñu
Lameck Chirwa
Thijs W. Hoffman
Owen Ngalamika
Sarah Lou Bailey
spellingShingle Sombo Fwoloshi
Lottie M. Hachaambwa
Kaseya O. Chiyeñu
Lameck Chirwa
Thijs W. Hoffman
Owen Ngalamika
Sarah Lou Bailey
Screening for Diabetes Mellitus among Tuberculosis Patients: Findings from a Study at a Tertiary Hospital in Lusaka, Zambia
Canadian Journal of Infectious Diseases and Medical Microbiology
author_facet Sombo Fwoloshi
Lottie M. Hachaambwa
Kaseya O. Chiyeñu
Lameck Chirwa
Thijs W. Hoffman
Owen Ngalamika
Sarah Lou Bailey
author_sort Sombo Fwoloshi
title Screening for Diabetes Mellitus among Tuberculosis Patients: Findings from a Study at a Tertiary Hospital in Lusaka, Zambia
title_short Screening for Diabetes Mellitus among Tuberculosis Patients: Findings from a Study at a Tertiary Hospital in Lusaka, Zambia
title_full Screening for Diabetes Mellitus among Tuberculosis Patients: Findings from a Study at a Tertiary Hospital in Lusaka, Zambia
title_fullStr Screening for Diabetes Mellitus among Tuberculosis Patients: Findings from a Study at a Tertiary Hospital in Lusaka, Zambia
title_full_unstemmed Screening for Diabetes Mellitus among Tuberculosis Patients: Findings from a Study at a Tertiary Hospital in Lusaka, Zambia
title_sort screening for diabetes mellitus among tuberculosis patients: findings from a study at a tertiary hospital in lusaka, zambia
publisher Hindawi Limited
series Canadian Journal of Infectious Diseases and Medical Microbiology
issn 1712-9532
1918-1493
publishDate 2018-01-01
description Background. Diabetes mellitus (DM) is known to be associated with active tuberculosis (TB). Zambia is a low-income sub-Saharan African country with a high TB burden and increasing numbers of newly diagnosed DM patients. Materials and Methods. This was an observational study conducted at the University Teaching Hospital in Lusaka, Zambia, from October 2014 to February 2016. Adult patients with active TB were screened for DM. Results. A total of 127 individuals were enrolled in the study. Six patients (5%) were found to have diabetes. Of these, three had a prior diagnosis of diabetes and were on medication while three were newly diagnosed. Low education level was significantly associated with DM (p=0.001; 95% CI 0.001–0.148). Conclusion. The prevalence of DM among individuals with smear positive TB in our study population was similar to that of the general population in Zambia.
url http://dx.doi.org/10.1155/2018/3524926
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