Heredity Indexes for Estimating Heritability Using Known and Unknown Family Data Based on the Model of Polygenic Inheritance

Objective. To establish a model for estimating genetic risk using known and unknown family data. Methods. Four simulated datasets were generated for four paternal and maternal chromosomes. The simulated data for children were generated from the parental data according to the Mendelian law. The corre...

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Bibliographic Details
Main Author: Hui Liu
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2020/7243976