A generic system for the expression and purification of soluble and stable influenza neuraminidase.
The influenza surface glycoprotein neuraminidase (NA) is essential for the efficient spread of the virus. Antiviral drugs such as Tamiflu (oseltamivir) and Relenza (zanamivir) that inhibit NA enzyme activity have been shown to be effective in the treatment of influenza infections. The recent 's...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-02-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3034727?pdf=render |