Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices

Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices

Single quantum dot tracking is an established technique used in cultured neurons and organotypic brain slices. Here, the authors demonstrate in vivotargeting of dopamine receptors via ventricular injection of functionalized quantum dots and track single nanoparticle-receptors in acute rat brain slic...

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Main Authors: Juan A. Varela, Julien P. Dupuis, Laetitia Etchepare, Agnès Espana, Laurent Cognet, Laurent Groc
Format: Article
Language:English
Published: Nature Publishing Group 2016-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10947
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spelling doaj-4af0862705e14546b4113f92197de36a2021-05-11T10:53:39ZengNature Publishing GroupNature Communications2041-17232016-03-017111010.1038/ncomms10947Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slicesJuan A. Varela0Julien P. Dupuis1Laetitia Etchepare2Agnès Espana3Laurent Cognet4Laurent Groc5University of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297University of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297University of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297University of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297University of Bordeaux, LP2 NUMR 5298University of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297Single quantum dot tracking is an established technique used in cultured neurons and organotypic brain slices. Here, the authors demonstrate in vivotargeting of dopamine receptors via ventricular injection of functionalized quantum dots and track single nanoparticle-receptors in acute rat brain slices.https://doi.org/10.1038/ncomms10947
collection DOAJ
language English
format Article
sources DOAJ
author Juan A. Varela
Julien P. Dupuis
Laetitia Etchepare
Agnès Espana
Laurent Cognet
Laurent Groc
spellingShingle Juan A. Varela
Julien P. Dupuis
Laetitia Etchepare
Agnès Espana
Laurent Cognet
Laurent Groc
Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices
Nature Communications
author_facet Juan A. Varela
Julien P. Dupuis
Laetitia Etchepare
Agnès Espana
Laurent Cognet
Laurent Groc
author_sort Juan A. Varela
title Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices
title_short Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices
title_full Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices
title_fullStr Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices
title_full_unstemmed Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices
title_sort targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2016-03-01
description Single quantum dot tracking is an established technique used in cultured neurons and organotypic brain slices. Here, the authors demonstrate in vivotargeting of dopamine receptors via ventricular injection of functionalized quantum dots and track single nanoparticle-receptors in acute rat brain slices.
url https://doi.org/10.1038/ncomms10947
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