Deep sequencing of HPV16 genomes: A new high-throughput tool for exploring the carcinogenicity and natural history of HPV16 infection

Deep sequencing of HPV16 genomes: A new high-throughput tool for exploring the carcinogenicity and natural history of HPV16 infection

For unknown reasons, there is huge variability in risk conferred by different HPV types and, remarkably, strong differences even between closely related variant lineages within each type. HPV16 is a uniquely powerful carcinogenic type, causing approximately half of cervical cancer and most other HPV...

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Bibliographic Details
Main Authors: Michael Cullen, Joseph F. Boland, Mark Schiffman, Xijun Zhang, Nicolas Wentzensen, Qi Yang, Zigui Chen, Kai Yu, Jason Mitchell, David Roberson, Sara Bass, Laurie Burdette, Moara Machado, Sarangan Ravichandran, Brian Luke, Mitchell J. Machiela, Mark Andersen, Matt Osentoski, Michael Laptewicz, Sholom Wacholder, Ashlie Feldman, Tina Raine-Bennett, Thomas Lorey, Philip E. Castle, Meredith Yeager, Robert D. Burk, Lisa Mirabello
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Papillomavirus Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2405852115000051

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http://www.sciencedirect.com/science/article/pii/S2405852115000051

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