Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor

<p>Abstract</p> <p>Background</p> <p>Hypoxia regulates gene expression via the transcription factor HIF (Hypoxia-Inducible Factor). Little is known regarding HIF expression and function in primary bone sarcomas. We describe HIF expression and phenotypic effects of hypox...

Full description

Bibliographic Details
Main Authors: Dirksen Uta, Schaefer Karl-Ludwig, Knowles Helen J, Athanasou Nicholas A
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/372