Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models
α-Conotoxins from <i>Conus</i> snails are capable of distinguishing muscle and neuronal nicotinic acetylcholine receptors (nAChRs). α-Conotoxin RgIA and αO-conotoxin GeXIVA, blocking neuronal α9α10 nAChR, are potential analgesics. Typically, &...
Main Authors: | Elena V. Kryukova, Igor A. Ivanov, Dmitry S. Lebedev, Ekaterina N. Spirova, Natalia S. Egorova, Marios Zouridakis, Igor E. Kasheverov, Socrates J. Tzartos, Victor I. Tsetlin |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-11-01
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Series: | Marine Drugs |
Subjects: | |
Online Access: | https://www.mdpi.com/1660-3397/16/12/460 |
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