Calcium Handling Defects and Cardiac Arrhythmia Syndromes

Calcium ions (Ca2+) play a major role in the cardiac excitation-contraction coupling. Intracellular Ca2+ concentration increases during systole and falls in diastole thereby determining cardiac contraction and relaxation. Normal cardiac function also requires perfect organization of the ion currents...

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Bibliographic Details
Main Authors: Kornél Kistamás, Roland Veress, Balázs Horváth, Tamás Bányász, Péter P. Nánási, David A. Eisner
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00072/full