Antibodies against a surface protein of Streptococcus pyogenes promote a pathological inflammatory response.

Antibodies against a surface protein of Streptococcus pyogenes promote a pathological inflammatory response.

Streptococcal toxic shock syndrome (STSS) caused by Streptococcus pyogenes is a clinical condition with a high mortality rate despite modern intensive care. A key feature of STSS is excessive plasma leakage leading to hypovolemic hypotension, disturbed microcirculation and multiorgan failure. Previo...

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Bibliographic Details
Main Authors: Fredrik Kahn, Matthias Mörgelin, Oonagh Shannon, Anna Norrby-Teglund, Heiko Herwald, Anders I Olin, Lars Björck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2522270?pdf=render

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http://europepmc.org/articles/PMC2522270?pdf=render

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