Regulation of DNA Replication Licensing and Re-Replication by Cdt1
In eukaryotic cells, DNA replication licensing is precisely regulated to ensure that the initiation of genomic DNA replication in S phase occurs once and only once for each mitotic cell division. A key regulatory mechanism by which DNA re-replication is suppressed is the S phase-dependent proteolysi...
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Format: | Article |
Language: | English |
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MDPI AG
2021-05-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | https://www.mdpi.com/1422-0067/22/10/5195 |