Differential regulation of matrix-metalloproteinases and their tissue inhibitors in patients with aneurysmal subarachnoid hemorrhage.

Differential regulation of matrix-metalloproteinases and their tissue inhibitors in patients with aneurysmal subarachnoid hemorrhage.

BACKGROUND: Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are involved in vascular remodeling, (neuro)inflammation, blood-brain barrier breakdown and neuronal apoptosis. Proinflammatory mechanisms are suggested to play an important role during early brain injury and cerebral v...

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Bibliographic Details
Main Authors: Marlene Fischer, Anelia Dietmann, Ronny Beer, Gregor Broessner, Raimund Helbok, Bettina Pfausler, Erich Schmutzhard, Peter Lackner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3610709?pdf=render

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http://europepmc.org/articles/PMC3610709?pdf=render

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