Helicobacter pylori Infection Causes Characteristic DNA Damage Patterns in Human Cells

Infection with the human pathogen Helicobacter pylori (H. pylori) is a major risk factor for gastric cancer. Since the bacterium exerts multiple genotoxic effects, we examined the circumstances of DNA damage accumulation and identified regions within the host genome with high susceptibility to H. py...

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Bibliographic Details
Main Authors: Max Koeppel, Fernando Garcia-Alcalde, Frithjof Glowinski, Philipp Schlaermann, Thomas F. Meyer
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715005665