Low-Dose Acetylsalicylic Acid Use and the Risk of Upper Gastrointestinal Bleeding: A Meta-Analysis of Randomized Clinical Trials and Observational Studies

BACKGROUND: Low-dose acetylsalicylic acid (LDA, 75 mg/day to 325 mg/day) is recommended for primary and secondary prevention of cardiovascular events, but has been linked to an increased risk of upper gastrointestinal bleeding (UGIB).

Bibliographic Details
Main Authors: Vera E Valkhoff, Miriam CJM Sturkenboom, Catherine Hill, Sander Veldhuyzen van Zanten, Ernst J Kuipers
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2013/596015