Two weeks of western diet disrupts liver molecular markers of cholesterol metabolism in rats

Two weeks of western diet disrupts liver molecular markers of cholesterol metabolism in rats

Abstract Background The present study was designed to test the hypothesis that in the liver, excessive fat accumulation impairs cholesterol metabolism mainly by altering the low-density lipoprotein-receptor (LDL-R) pathway. Method Young male Wistar rats were fed standard (SD), high fat (HFD; 60% kca...

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Bibliographic Details
Main Authors: Roxane St-Amand, Émilienne T. Ngo Sock, Samantha Quinn, Jean-Marc Lavoie, David H. St-Pierre
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Lipids in Health and Disease
Subjects:
Western diet
Plasma cholesterol
Lipogenesis
Hepatic steatosis
Liver cholesterol metabolism
Low-density lipoprotein-receptor
Online Access:http://link.springer.com/article/10.1186/s12944-020-01351-2

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http://link.springer.com/article/10.1186/s12944-020-01351-2

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