Toxoplasmosis in rodents: A systematic review and meta-analysis in Iran

During recent years, implication of rodents in the epidemiology of Toxoplasma gondii is overlooked in Iran; thus, we performed a systematic review and meta-analysis to evaluate the prevalence of toxoplasmosis in rodents of Iran. For this purpose, following the general methodology recommended for sys...

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Main Authors: Shahram Khademvatan, Masoud Foroutan, Khosrow Hazrati-Tappeh, Sahar Dalvand, Hamidreza Khalkhali, Sajjad Masoumifard, Faezeh Hedayati-Rad
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Journal of Infection and Public Health
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034117300564
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spelling doaj-4de9bbeb09254f938d22192bd772e9512020-11-24T21:39:13ZengElsevierJournal of Infection and Public Health1876-03412017-09-01105487493Toxoplasmosis in rodents: A systematic review and meta-analysis in IranShahram Khademvatan0Masoud Foroutan1Khosrow Hazrati-Tappeh2Sahar Dalvand3Hamidreza Khalkhali4Sajjad Masoumifard5Faezeh Hedayati-Rad6Cellular and Molecular Research Center & Department of Medical Parasitology and Mycology, Urmia University of Medical Sciences, Urmia, IranDepartment of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran; Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran; Corresponding author at: Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, & Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran.Cellular and Molecular Research Center & Department of Medical Parasitology and Mycology, Urmia University of Medical Sciences, Urmia, IranSocial Determinants of Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, IranInpatient’s Safety Research Center, Urmia University of Medical Sciences, Urmia, IranStudent Research Committee, Urmia University of Medical Sciences, Urmia, IranDepartment of Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran; Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran; Corresponding author at: Department of Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, & Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran.During recent years, implication of rodents in the epidemiology of Toxoplasma gondii is overlooked in Iran; thus, we performed a systematic review and meta-analysis to evaluate the prevalence of toxoplasmosis in rodents of Iran. For this purpose, following the general methodology recommended for systematic reviews and meta-analysis, 5 English and 3 Persian databases were explored from 1 January 2000 till 10 September 2016 using related keywords. Finally, 9 out of 291 citations were met to be included in this study. Due to significant heterogeneity, the random-effects model was conducted (I2 = 93.55%). During the years, 661 rodents were trapped, and 121 of them were identified positive for T. gondii 15% (95% CI = 5–27). Moreover, overall prevalence using direct microscopic examination (1/230), PCR-based techniques (41/246) and serological tests (83/437) was obtained 0.1% (95% CI = 0.0–1.5), 18% (95% CI = 4–39) and 15% (95% CI = 3–33), respectively. Our study revealed the prevalence of toxoplasmosis in rodents is remarkable. Considering this fact, they play a key role in the life cycle of T. gondii and should not be neglected. Further surveys is needed to better recognize the role of various rodent species in distribution of toxoplasmosis. Keywords: Toxoplasma gondii, Rodents, Systematic review, Meta-analysis, Iranhttp://www.sciencedirect.com/science/article/pii/S1876034117300564
collection DOAJ
language English
format Article
sources DOAJ
author Shahram Khademvatan
Masoud Foroutan
Khosrow Hazrati-Tappeh
Sahar Dalvand
Hamidreza Khalkhali
Sajjad Masoumifard
Faezeh Hedayati-Rad
spellingShingle Shahram Khademvatan
Masoud Foroutan
Khosrow Hazrati-Tappeh
Sahar Dalvand
Hamidreza Khalkhali
Sajjad Masoumifard
Faezeh Hedayati-Rad
Toxoplasmosis in rodents: A systematic review and meta-analysis in Iran
Journal of Infection and Public Health
author_facet Shahram Khademvatan
Masoud Foroutan
Khosrow Hazrati-Tappeh
Sahar Dalvand
Hamidreza Khalkhali
Sajjad Masoumifard
Faezeh Hedayati-Rad
author_sort Shahram Khademvatan
title Toxoplasmosis in rodents: A systematic review and meta-analysis in Iran
title_short Toxoplasmosis in rodents: A systematic review and meta-analysis in Iran
title_full Toxoplasmosis in rodents: A systematic review and meta-analysis in Iran
title_fullStr Toxoplasmosis in rodents: A systematic review and meta-analysis in Iran
title_full_unstemmed Toxoplasmosis in rodents: A systematic review and meta-analysis in Iran
title_sort toxoplasmosis in rodents: a systematic review and meta-analysis in iran
publisher Elsevier
series Journal of Infection and Public Health
issn 1876-0341
publishDate 2017-09-01
description During recent years, implication of rodents in the epidemiology of Toxoplasma gondii is overlooked in Iran; thus, we performed a systematic review and meta-analysis to evaluate the prevalence of toxoplasmosis in rodents of Iran. For this purpose, following the general methodology recommended for systematic reviews and meta-analysis, 5 English and 3 Persian databases were explored from 1 January 2000 till 10 September 2016 using related keywords. Finally, 9 out of 291 citations were met to be included in this study. Due to significant heterogeneity, the random-effects model was conducted (I2 = 93.55%). During the years, 661 rodents were trapped, and 121 of them were identified positive for T. gondii 15% (95% CI = 5–27). Moreover, overall prevalence using direct microscopic examination (1/230), PCR-based techniques (41/246) and serological tests (83/437) was obtained 0.1% (95% CI = 0.0–1.5), 18% (95% CI = 4–39) and 15% (95% CI = 3–33), respectively. Our study revealed the prevalence of toxoplasmosis in rodents is remarkable. Considering this fact, they play a key role in the life cycle of T. gondii and should not be neglected. Further surveys is needed to better recognize the role of various rodent species in distribution of toxoplasmosis. Keywords: Toxoplasma gondii, Rodents, Systematic review, Meta-analysis, Iran
url http://www.sciencedirect.com/science/article/pii/S1876034117300564
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