Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling
A variety of ligands differ in their capacity to bind the receptor, elicit gene expression, and modulate physiological responses. Such receptors include Toll-like receptors (TLRs), which recognize various patterns of pathogens and lead to primary innate immune activation against invaders, and G-prot...
Main Authors: | Jayalakshmi Krishnan, Sangdun Choi |
---|---|
Format: | Article |
Language: | English |
Published: |
Korea Genome Organization
2012-09-01
|
Series: | Genomics & Informatics |
Subjects: | |
Online Access: | http://genominfo.org/upload/pdf/gni-10-153.pdf |
Similar Items
-
Coactivation of TLR2 and TLR8 in Primary Human Monocytes Triggers a Distinct Inflammatory Signaling Response
by: Korbinian Bösl, et al.
Published: (2018-05-01) -
Early p38 Activation Regulated by MKP-1 Is Determinant for High Levels of IL-10 Expression Through TLR2 Activation
by: Sara Francisco, et al.
Published: (2021-06-01) -
Similar structures but different roles - An updated perspective on TLR structures
by: Balachandran eManavalan, et al.
Published: (2011-07-01) -
TLR‐2 and TLR‐4 expression in monocytes of newborns with late‐onset sepsis
by: Ana C.C. Redondo, et al.
Published: (2014-09-01) -
Astroglial TLR9 antagonism promotes chemotaxis and alternative activation of macrophages via modulation of astrocyte-derived signals: implications for spinal cord injury
by: Lun Li, et al.
Published: (2020-02-01)