Association of DNA Methylation at CPT1A Locus with Metabolic Syndrome in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Study.

Association of DNA Methylation at CPT1A Locus with Metabolic Syndrome in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Study.

In this study, we conducted an epigenome-wide association study of metabolic syndrome (MetS) among 846 participants of European descent in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN). DNA was isolated from CD4+ T cells and methylation at ~470,000 cytosine-phosphate-guanine dinucleo...

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Bibliographic Details
Main Authors: Mithun Das, Jin Sha, Bertha Hidalgo, Stella Aslibekyan, Anh N Do, Degui Zhi, Dianjianyi Sun, Tao Zhang, Shengxu Li, Wei Chen, Sathanur R Srinivasan, Hemant K Tiwari, Devin Absher, Jose M Ordovas, Gerald S Berenson, Donna K Arnett, Marguerite R Irvin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4726462?pdf=render

Internet

http://europepmc.org/articles/PMC4726462?pdf=render

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