Cyclic Mechanical Stretching Induces Autophagic Cell Death in Tenofibroblasts Through Activation of Prostaglandin E2 Production

Cyclic Mechanical Stretching Induces Autophagic Cell Death in Tenofibroblasts Through Activation of Prostaglandin E2 Production

Background/Aims: Autophagic cell death has recently been implicated in the pathophysiology of tendinopathy. Prostaglandin E2 (PGE2), a known inflammatory mediator of tendinitis, inhibits tenofibroblast proliferation in vitro; however, the underlying mechanism is unclear. The present study investigat...

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Bibliographic Details
Main Authors: Hua Chen, Liyang Chen, Biao Cheng, Chaoyin Jiang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Prostaglandin E2
Autophagy
Cell death
Tendinopathy
Online Access:http://www.karger.com/Article/FullText/374050

Internet

http://www.karger.com/Article/FullText/374050

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