Mesenchymal Stromal Cell-Derived Extracellular Vesicles Attenuate Dendritic Cell Maturation and Function

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Attenuate Dendritic Cell Maturation and Function

Mesenchymal stromal cells (MSCs) are potent regulators of immune responses largely through paracrine signaling. MSC secreted extracellular vesicles (MSC-EVs) are increasingly recognized as the key paracrine factors responsible for the biological and therapeutic function of MSCs. We report the first...

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Bibliographic Details
Main Authors: Monica Reis, Emily Mavin, Lindsay Nicholson, Kile Green, Anne M. Dickinson, Xiao-nong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
extracellular vesicles
mesenchymal stromal cells
immunomodulation
dendritic cells
microRNA
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02538/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02538/full

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