International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impactResearch in context

International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impactResearch in context

Background: Pneumococcal conjugate vaccines have reduced the incidence of invasive pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a concern. We used whole genome sequencing to study pneumococcal serotype, antibiotic resistance and invasiveness, in the context of...

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Main Authors: Rebecca A. Gladstone, Stephanie W. Lo, John A. Lees, Nicholas J. Croucher, Andries J. van Tonder, Jukka Corander, Andrew J. Page, Pekka Marttinen, Leon J. Bentley, Theresa J. Ochoa, Pak Leung Ho, Mignon du Plessis, Jennifer E. Cornick, Brenda Kwambana-Adams, Rachel Benisty, Susan A. Nzenze, Shabir A. Madhi, Paulina A. Hawkins, Dean B. Everett, Martin Antonio, Ron Dagan, Keith P. Klugman, Anne von Gottberg, Lesley McGee, Robert F. Breiman, Stephen D. Bentley
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419302592

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http://www.sciencedirect.com/science/article/pii/S2352396419302592

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