Assessing pooled BAC and whole genome shotgun strategies for assembly of complex genomes
<p>Abstract</p> <p>Background</p> <p>We investigate if pooling BAC clones and sequencing the pools can provide for more accurate assembly of genome sequences than the "whole genome shotgun" (WGS) approach. Furthermore, we quantify this accuracy increase. We co...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-04-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/12/194 |