Protopanaxatriol-type saponin protects against acetaminophen-induced liver injury through ROS-mediated JNK pathway

Protopanaxatriol-type saponin protects against acetaminophen-induced liver injury through ROS-mediated JNK pathway

Worldwide, drug-induced acute liver failure is associated with a high rate of morbidity and mortality. Acetaminophen (APAP), a widely used analgesic, is one of the most common causes of acute liver injury. The purpose of this study was to determine the protective effect of protopanaxatriol-type sapo...

Full description

Bibliographic Details
Main Authors: Linlin Qu, Rongzhan Fu, Xiaoxuan Ma, Daidi Fan
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Journal of Functional Foods
Subjects:
Acetaminophen
Protopanaxatriol-type saponin
Inflammation
Oxidative stress
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621003212

Internet

http://www.sciencedirect.com/science/article/pii/S1756464621003212

Similar Items