Hemogenic Endothelial Cells Can Transition to Hematopoietic Stem Cells through a B-1 Lymphocyte-Biased State during Maturation in the Mouse Embryo

Summary: Precursors of hematopoietic stem cells (pre-HSCs) have been identified as intermediate precursors during the maturation process from hemogenic endothelial cells to HSCs in the aorta-gonad-mesonephros (AGM) region of the mouse embryo at embryonic day 10.5. Although pre-HSCs acquire an effici...

Full description

Bibliographic Details
Main Authors: Michihiro Kobayashi, Stefan P. Tarnawsky, Haichao Wei, Akansha Mishra, Nathalia Azevedo Portilho, Pamela Wenzel, Brian Davis, Jiaqian Wu, Brandon Hadland, Momoko Yoshimoto
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119301936