Structure, Activation and Regulation of NLRP3 and AIM2 Inflammasomes

Structure, Activation and Regulation of NLRP3 and AIM2 Inflammasomes

<b>: </b>The inflammasome is a three-component (sensor, adaptor, and effector) filamentous signaling platform that shields from multiple pathogenic infections by stimulating the proteolytical maturation of proinflammatory cytokines and pyroptotic cell death. The signaling process initiat...

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Bibliographic Details
Main Authors: Meenakshi Sharma, Eva de Alba
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
inflammation
ASC (apoptosis-associated speck-like protein containing a CARD)
NLRP3
AIM2
NMR
protein structure
Online Access:https://www.mdpi.com/1422-0067/22/2/872

Internet

https://www.mdpi.com/1422-0067/22/2/872

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