Why tyrosine kinase inhibitor resistance is common in advanced gastrointestinal stromal tumors [v1; ref status: indexed, http://f1000r.es/1ac]
Background: Most patients with advanced gastrointestinal stromal tumors (GIST) develop drug resistance to tyrosine kinase inhibitors (TKIs) within two years of starting therapy, whereas most chronic myeloid leukemia (CML) patients in chronic phase still exhibit disease control after a decade on ther...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2013-07-01
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Series: | F1000Research |
Subjects: | |
Online Access: | http://f1000research.com/articles/2-152/v1 |