Topological analysis of MAPK cascade for kinetic ErbB signaling.

Topological analysis of MAPK cascade for kinetic ErbB signaling.

Ligand-induced homo- and hetero-dimer formation of ErbB receptors results in different biological outcomes irrespective of recruitment and activation of similar effector proteins. Earlier experimental research indicated that cells expressing both EGFR (epidermal growth factor receptor) and the ErbB4...

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Bibliographic Details
Main Authors: Takashi Nakakuki, Noriko Yumoto, Takashi Naka, Mikako Shirouzu, Shigeyuki Yokoyama, Mariko Hatakeyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2262155?pdf=render

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http://europepmc.org/articles/PMC2262155?pdf=render

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