Characterisation of a highly potent and near pan-neutralising anti-HIV monoclonal antibody expressed in tobacco plants

Characterisation of a highly potent and near pan-neutralising anti-HIV monoclonal antibody expressed in tobacco plants

Abstract Background HIV remains one of the most important health issues worldwide, with almost 40 million people living with HIV. Although patients develop antibodies against the virus, its high mutation rate allows evasion of immune responses. Some patients, however, produce antibodies that are abl...

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Bibliographic Details
Main Authors: Catherine M. Moore, Melanie Grandits, Clemens Grünwald-Gruber, Friedrich Altmann, Maria Kotouckova, Audrey Y.-H. Teh, Julian K.-C. Ma
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Retrovirology
Subjects:
HIV
Monoclonal antibodies
bNAbs
Plants
Molecular pharming
Immunotherapy
Online Access:https://doi.org/10.1186/s12977-021-00560-6

Internet

https://doi.org/10.1186/s12977-021-00560-6

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