A ligand channel through the G protein coupled receptor opsin.

A ligand channel through the G protein coupled receptor opsin.

The G protein coupled receptor rhodopsin contains a pocket within its seven-transmembrane helix (TM) structure, which bears the inactivating 11-cis-retinal bound by a protonated Schiff-base to Lys296 in TM7. Light-induced 11-cis-/all-trans-isomerization leads to the Schiff-base deprotonated active M...

Full description

Bibliographic Details
Main Authors: Peter W Hildebrand, Patrick Scheerer, Jung Hee Park, Hui-Woog Choe, Ronny Piechnick, Oliver P Ernst, Klaus Peter Hofmann, Martin Heck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2632885?pdf=render

Internet

http://europepmc.org/articles/PMC2632885?pdf=render

Similar Items