Sulforaphane Modulates Joint Inflammation in a Murine Model of Complete Freund’s Adjuvant-Induced Mono-Arthritis

Sulforaphane Modulates Joint Inflammation in a Murine Model of Complete Freund’s Adjuvant-Induced Mono-Arthritis

Rheumatoid arthritis (RA) is characterized by inflammation of one or more joints, and affects ~1% of the adult population worldwide. Sulforaphane (SFN) is a natural compound that has been suggested as an antioxidant. Here, SFN’s effects were evaluated in a murine mono-arthritis model. Mono...

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Bibliographic Details
Main Authors: João Francisco Silva Rodrigues, Cristiane Silva e Silva, Thayanne França Muniz, Alana Fernanda de Aquino, Larissa Neuza da Silva Nina, Nagila Caroline Fialho Sousa, Luis Claudio Nascimento da Silva, Breno Glaessner Gomes Fernandes de Souza, Tatiana Aranha da Penha, Ana Lúcia Abreu-Silva, Joicy Cortez de Sá, Elizabeth Soares Fernandes, Marcos Augusto Grigolin Grisotto
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Molecules
Subjects:
rheumatoid arthritis
sulforaphane
oedema
IL-6
thioredoxin reductase
Online Access:http://www.mdpi.com/1420-3049/23/5/988

Internet

http://www.mdpi.com/1420-3049/23/5/988

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