Menadione (vitamin K) enhances the antibiotic activity of drugs by cell membrane permeabilization mechanism

Menadione (vitamin K) enhances the antibiotic activity of drugs by cell membrane permeabilization mechanism

Menadione, vitamin K3, belongs to the class of lipid-soluble vitamins and lipophilic substances as menadione cause disturbances in the bacterial membrane, resulting in damage to the fundamental elements for the integrity of the membrane, thus allowing increased permeability. Accordingly, the aim of...

Full description

Bibliographic Details
Main Authors: Jacqueline C. Andrade, Maria Flaviana B. Morais Braga, Gláucia Morgana M. Guedes, Saulo R. Tintino, Maria A. Freitas, Lucindo J. Quintans, Jr., Irwin R.A. Menezes, Henrique D.M. Coutinho
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Saudi Journal of Biological Sciences
Subjects:
Menadione
Lipid solubility
Microdilution
Antibiotic-modifying
Permeabilization
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X15001990

Internet

http://www.sciencedirect.com/science/article/pii/S1319562X15001990

Similar Items