Differential Impact of miR-21 on Pain and Associated Affective and Cognitive Behavior after Spared Nerve Injury in B7-H1 ko Mouse

MicroRNAs (miRNAs) are increasingly recognized as regulators of immune and neuronal gene expression and are potential master switches in neuropathic pain pathophysiology. miR-21 is a promising candidate that may link the immune and the pain system. To investigate the pathophysiological role of miR-2...

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Bibliographic Details
Main Authors: Franziska Karl, Anne Grießhammer, Nurcan Üçeyler, Claudia Sommer
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
SNI
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00219/full