T Cell Receptor Expression Timing and Signal Strength in the Functional Differentiation of Invariant Natural Killer T Cells

T Cell Receptor Expression Timing and Signal Strength in the Functional Differentiation of Invariant Natural Killer T Cells

The CD1d-restricted Vα14 invariant NKT (iNKT) cell lineage in mice (Vα24 in humans) represents an evolutionary conserved innate-like immune cell type that recognizes glycolipid antigens. Because of their unique ability to promptly secrete copious amounts of both pro-inflammatory and anti-inflammator...

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Bibliographic Details
Main Authors: Nyambayar Dashtsoodol, Sabrina Bortoluzzi, Marc Schmidt-Supprian
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
NKT
CD1d
lymphocyte
development
functional subset
thymus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00841/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00841/full

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