A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR

A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR

Chimeric antigen receptor (CAR) T cells have shown impressive therapeutic potential. Due to the lack of direct control mechanisms, therapy-related adverse reactions including cytokine release- and tumor lysis syndrome can even become life-threatening. In case of target antigen expression on non-mali...

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Bibliographic Details
Main Authors: Claudia Arndt, Anja Feldmann, Stefanie Koristka, Martin Schäfer, Ralf Bergmann, Nicola Mitwasi, Nicole Berndt, Dominik Bachmann, Alexandra Kegler, Marc Schmitz, Edinson Puentes-Cala, Javier Andrés Soto, Gerhard Ehninger, Jens Pietzsch, Christos Liolios, Gerd Wunderlich, Jörg Kotzerke, Klaus Kopka, Michael Bachmann
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:OncoImmunology
Subjects:
psma ligand
unicar
prostate cancer
immunotherapy
pet imaging
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1659095

Internet

http://dx.doi.org/10.1080/2162402X.2019.1659095

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