Physical Interaction of T Cells with Dendritic Cells is not Required for the Immunomodulatory Effects of the Edible Mushroom Agaricus subrufescens

Mushrooms are well known for their immunomodulating capacities. However, little is known about how mushroom-stimulated dendritic cells (DCs) affect T cells. Therefore we investigated the effect of mushroom compounds derived from seven edible mushroom species on DCs, their fate in DCs and the effect...

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Bibliographic Details
Main Authors: Ruud Wilbers, Lotte Westerhof, Jan Van De Velde, Geert Smant, Debbie van Raaij, Anton Sonnenberg, Jaap Bakker, Arjen Schots
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Immunology
Subjects:
PRR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00519/full