In vivo imaging of mGluR5 changes during epileptogenesis using [11C]ABP688 PET in pilocarpine-induced epilepsy rat model.

In vivo imaging of mGluR5 changes during epileptogenesis using [11C]ABP688 PET in pilocarpine-induced epilepsy rat model.

Metabotropic glutamate receptor 5 (mGluR5) that regulates glutamatergic neurotransmission contributes to pathophysiology of epilepsy. In this study, we monitored the changes of mGluR5 in vivo using [11C]ABP688 PET during the epileptogenesis in a pilocarpine-induced epilepsy rat model.In vivo mGluR5...

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Bibliographic Details
Main Authors: Hongyoon Choi, Yu Kyeong Kim, So Won Oh, Hyung-Jun Im, Do Won Hwang, Hyejin Kang, Boeun Lee, Yun-Sang Lee, Jae Min Jeong, E Edmund Kim, June-Key Chung, Dong Soo Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3963947?pdf=render

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http://europepmc.org/articles/PMC3963947?pdf=render

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