Attenuated Recovery of Contractile Function in Aging Hearts Following Global Ischemia/Reperfusion: Role of Extracellular HSP27 and TLR4
Abstract While cardiac functional recovery is attenuated in the elderly following cardiac surgery with obligatory global myocardial ischemia/reperfusion (I/R), the underlying mechanism remains incompletely understood. We observed previously that human and mouse myocardium releases heat shock protein...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2016-12-01
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Series: | Molecular Medicine |
Online Access: | http://link.springer.com/article/10.2119/molmed.2016.00204 |