Arsenic, Cadmium and Lead Exposure and Immunologic Function in Workers in Taiwan

There has been growing concern over the impact of environmental exposure to heavy metals and other trace elements on immunologic functions. This study investigated men’s arsenic (As), cadmium (Cd) and lead (Pb) contents in hair samples and their associations with immunological indicators, including...

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Main Authors: Chin-Ching Wu, Fung-Chang Sung, Yi-Chun Chen
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Environmental Research and Public Health
Subjects:
Online Access:http://www.mdpi.com/1660-4601/15/4/683
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spelling doaj-54ff8541450b4f1a8574359cf5e3c2e92020-11-24T20:40:36ZengMDPI AGInternational Journal of Environmental Research and Public Health1660-46012018-04-0115468310.3390/ijerph15040683ijerph15040683Arsenic, Cadmium and Lead Exposure and Immunologic Function in Workers in TaiwanChin-Ching Wu0Fung-Chang Sung1Yi-Chun Chen2Department of Public Health, China Medical University, 91 Hsueh-Shih Road, Taichung 404, TaiwanDepartment of Health Services Administration, China Medical University, 91 Hsueh-Shih Road, Taichung 404, TaiwanDepartment of Health Management, College of Medicine, I-Shou University, 8 Yida Road, Yanchao District, Kaohsiung 824, TaiwanThere has been growing concern over the impact of environmental exposure to heavy metals and other trace elements on immunologic functions. This study investigated men’s arsenic (As), cadmium (Cd) and lead (Pb) contents in hair samples and their associations with immunological indicators, including white blood cell (WBC), lymphocyte and monocyte counts, and the immunoglobulin (Ig) levels including IgA, IgG and IgE. We recruited 133 men from one antimony trioxide manufacturing plant, two glass manufacturing plants and two plastics manufacturing plants. The mean concentration of Cd [0.16 (SD = 0.03) ug/g] was lower than means of As [0.86 (SD = 0.16) ug/g] and Pb [0.91 (SD = 0.22) ug/g] in hair samples, exerting no relationship with immunologic functions for Cd. The Spearman’s correlation analysis showed a positive relationship between monocyte counts and hair Pb levels, but negative relations between As and IgG and between As and IgE. In conclusion, findings from these industry workers suggest that As levels in hair may have a stronger relation with immunologic function than Cd and PB have. Further research is needed to confirm the negative relationship.http://www.mdpi.com/1660-4601/15/4/683arseniccadmiumleadhairimmunologic function
collection DOAJ
language English
format Article
sources DOAJ
author Chin-Ching Wu
Fung-Chang Sung
Yi-Chun Chen
spellingShingle Chin-Ching Wu
Fung-Chang Sung
Yi-Chun Chen
Arsenic, Cadmium and Lead Exposure and Immunologic Function in Workers in Taiwan
International Journal of Environmental Research and Public Health
arsenic
cadmium
lead
hair
immunologic function
author_facet Chin-Ching Wu
Fung-Chang Sung
Yi-Chun Chen
author_sort Chin-Ching Wu
title Arsenic, Cadmium and Lead Exposure and Immunologic Function in Workers in Taiwan
title_short Arsenic, Cadmium and Lead Exposure and Immunologic Function in Workers in Taiwan
title_full Arsenic, Cadmium and Lead Exposure and Immunologic Function in Workers in Taiwan
title_fullStr Arsenic, Cadmium and Lead Exposure and Immunologic Function in Workers in Taiwan
title_full_unstemmed Arsenic, Cadmium and Lead Exposure and Immunologic Function in Workers in Taiwan
title_sort arsenic, cadmium and lead exposure and immunologic function in workers in taiwan
publisher MDPI AG
series International Journal of Environmental Research and Public Health
issn 1660-4601
publishDate 2018-04-01
description There has been growing concern over the impact of environmental exposure to heavy metals and other trace elements on immunologic functions. This study investigated men’s arsenic (As), cadmium (Cd) and lead (Pb) contents in hair samples and their associations with immunological indicators, including white blood cell (WBC), lymphocyte and monocyte counts, and the immunoglobulin (Ig) levels including IgA, IgG and IgE. We recruited 133 men from one antimony trioxide manufacturing plant, two glass manufacturing plants and two plastics manufacturing plants. The mean concentration of Cd [0.16 (SD = 0.03) ug/g] was lower than means of As [0.86 (SD = 0.16) ug/g] and Pb [0.91 (SD = 0.22) ug/g] in hair samples, exerting no relationship with immunologic functions for Cd. The Spearman’s correlation analysis showed a positive relationship between monocyte counts and hair Pb levels, but negative relations between As and IgG and between As and IgE. In conclusion, findings from these industry workers suggest that As levels in hair may have a stronger relation with immunologic function than Cd and PB have. Further research is needed to confirm the negative relationship.
topic arsenic
cadmium
lead
hair
immunologic function
url http://www.mdpi.com/1660-4601/15/4/683
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AT yichunchen arseniccadmiumandleadexposureandimmunologicfunctioninworkersintaiwan
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