Meta-analysis of variation suggests that embracing variability improves both replicability and generalizability in preclinical research.

The replicability of research results has been a cause of increasing concern to the scientific community. The long-held belief that experimental standardization begets replicability has also been recently challenged, with the observation that the reduction of variability within studies can lead to i...

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Bibliographic Details
Main Authors: Takuji Usui, Malcolm R Macleod, Sarah K McCann, Alistair M Senior, Shinichi Nakagawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001009