Modulating Tumor-Associated Macrophage Polarization by Synthetic and Natural PPARγ Ligands as a Potential Target in Breast Cancer

Modulating Tumor-Associated Macrophage Polarization by Synthetic and Natural PPARγ Ligands as a Potential Target in Breast Cancer

Activation of peroxisome proliferator-activated receptor gamma (PPARγ) elicits anti-proliferative effects on different tumor cells, including those derived from breast cancer. PPARγ is also expressed in several cells of the breast tumor microenvironment, among which tumor associate...

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Bibliographic Details
Main Authors: Giulia Gionfriddo, Pierluigi Plastina, Giuseppina Augimeri, Stefania Catalano, Cinzia Giordano, Ines Barone, Catia Morelli, Francesca Giordano, Luca Gelsomino, Diego Sisci, Renger Witkamp, Sebastiano Andò, Klaske van Norren, Daniela Bonofiglio
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
tumor associated macrophages
breast tumor microenvironment
peroxisome proliferator-activated receptor gamma
<i>n</i>-3 polyunsaturated fatty acids
docosahexaenoyl ethanolamine (dhea)
docosahexaenoyl serotonin (dha-5-ht)
rosiglitazone
Online Access:https://www.mdpi.com/2073-4409/9/1/174

Internet

https://www.mdpi.com/2073-4409/9/1/174

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