Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals
Genome-wide association studies (GWASs) for cigarette smoking have identified several hundred loci that account for a small proportion of the overall genetic risk. Here, the authors report a large GWAS for smoking trajectories and meta-analysis for smoking status, finding multiple plausible loci.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2020-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-18489-3 |
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doaj-5636c1ee2c174d56952ba63ab531d333 |
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Article |
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doaj-5636c1ee2c174d56952ba63ab531d3332021-05-11T08:55:15ZengNature Publishing GroupNature Communications2041-17232020-10-0111111110.1038/s41467-020-18489-3Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individualsKe Xu0Boyang Li1Kathleen A. McGinnis2Rachel Vickers-Smith3Cecilia Dao4Ning Sun5Rachel L. Kember6Hang Zhou7William C. Becker8Joel Gelernter9Henry R. Kranzler10Hongyu Zhao11Amy C. Justice12VA Million Veteran ProgramYale School of MedicineVA Connecticut Healthcare SystemVA Connecticut Healthcare SystemUniversity of Kentucky College of Public HealthVA Connecticut Healthcare SystemYale School of Public HealthUniversity of Pennsylvania Perelman School of MedicineYale School of MedicineYale School of MedicineYale School of MedicineUniversity of Pennsylvania Perelman School of MedicineYale School of MedicineYale School of MedicineGenome-wide association studies (GWASs) for cigarette smoking have identified several hundred loci that account for a small proportion of the overall genetic risk. Here, the authors report a large GWAS for smoking trajectories and meta-analysis for smoking status, finding multiple plausible loci.https://doi.org/10.1038/s41467-020-18489-3 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Ke Xu Boyang Li Kathleen A. McGinnis Rachel Vickers-Smith Cecilia Dao Ning Sun Rachel L. Kember Hang Zhou William C. Becker Joel Gelernter Henry R. Kranzler Hongyu Zhao Amy C. Justice VA Million Veteran Program |
| spellingShingle |
Ke Xu Boyang Li Kathleen A. McGinnis Rachel Vickers-Smith Cecilia Dao Ning Sun Rachel L. Kember Hang Zhou William C. Becker Joel Gelernter Henry R. Kranzler Hongyu Zhao Amy C. Justice VA Million Veteran Program Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals Nature Communications |
| author_facet |
Ke Xu Boyang Li Kathleen A. McGinnis Rachel Vickers-Smith Cecilia Dao Ning Sun Rachel L. Kember Hang Zhou William C. Becker Joel Gelernter Henry R. Kranzler Hongyu Zhao Amy C. Justice VA Million Veteran Program |
| author_sort |
Ke Xu |
| title |
Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals |
| title_short |
Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals |
| title_full |
Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals |
| title_fullStr |
Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals |
| title_full_unstemmed |
Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals |
| title_sort |
genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2020-10-01 |
| description |
Genome-wide association studies (GWASs) for cigarette smoking have identified several hundred loci that account for a small proportion of the overall genetic risk. Here, the authors report a large GWAS for smoking trajectories and meta-analysis for smoking status, finding multiple plausible loci. |
| url |
https://doi.org/10.1038/s41467-020-18489-3 |
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