Synthesis of 1,4-dihydropyrimidines with immobilized urease: effect of method immobilization on magnetic supports

The effect of the urease immobilization method was studied on magnetic supports for the Biginelli/Hantzsch reaction. For this purpose, Fe3O4/SiO2 was modified with 3-aminopropyl-triethoxysilane and then activated with glutaraldehyde. A ratio of 500 mg of enzyme per gram of support at 4°C and 18 h we...

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Bibliographic Details
Main Authors: Vargas Annie Y., Rojas Hugo A., Romanelli Gustavo P., Martínez José J.
Format: Article
Language:English
Published: De Gruyter 2017-08-01
Series:Green Processing and Synthesis
Subjects:
Online Access:https://doi.org/10.1515/gps-2016-0143