Reduced somatostatin in subgenual anterior cingulate cortex in major depression

Converging evidence suggests a central role for dysfunction of the subgenual anterior cingulate cortex (sgACC) in the pathophysiology of major depressive disorder (MDD). Underlying mechanisms may include altered GABAergic function. Expression of somatostatin (SST), an inhibitory neuropeptide localiz...

Full description

Bibliographic Details
Main Authors: Adam Tripp, Rama S. Kota, David A. Lewis, Etienne Sibille
Format: Article
Language:English
Published: Elsevier 2011-04-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111000155